Mitochondrial membrane transport protein
Mitochondrial membrane transport proteins are proteins which exist in the membranes of mitochondria and which serve to transport molecules and other factors such as ions into or out of the organelles.
ExamplesExamples of mitochondrial transport proteins include the following:
- The mitochondrial permeability transition pore, which opens in response to increased mitochondrial calcium (Ca2+) load and oxidative stressCrompton M. 1999. The mitochondrial permeability transition pore and its role in cell death. Biochemical Journal. Volume 341, Pages 233-249. . Retrieved on January 23, 2007.
- The mitochondrial calcium uniporter which transports calcium from the cytosol of the cell into the mitochondrial matrixNicholls DG. 2005. Mitochondria and calcium signaling. Cell Calcium, Volume 38, Issues 3-4, Pages 311-317. . Retrieved on January 23, 2007.
- The mitochondrial sodium/calcium exchanger, which carries Ca2+ ions out of the matrix in exchange for Na+ ions. These transport proteins serve to maintain the proper electrical and chemical gradients in mitochondria by keeping ions and other factors in the right balance between the inside and outside of mitochondria.