An oncocyte is an epithelial cell characterized by an excessive number of mitochondria, resulting in an abundant acidophilic, granular cytoplasm. Oncocytes can be benign or malignant.
Other namesAlso known as:
- Hürthle cell ( thyroid gland only)
- Oxyphilic cell,
- Askanazy cell,
- Apocrine metaplasia (breast gland only).
EtymologyDerived from the Greek root onco-, which means mass, bulk.
- Oncocytoma, a tumour composed of oncocytes, may be found as a less common salivary gland neoplasm also known as Oxyphilic Adenoma.
- Renal oncocytoma, a kidney tumour composed of oncocytes.
- Hurthle cell carcinoma, a variant of follicular thyroid carcinoma).